Objective: The aim of the study is to investigate anti-Mullerian hormone levels after laparotomic myomectomy and the pregnancy outcomes for these infertile patients.
Methods: Forty-seven patients aged 20 to 40 who underwent abdominal myomectomy between October 2017-October 2018 were evaluated retrospectively. Pre-post-operative serum Anti-mullerian hormone (AMH) levels, complete blood count (CBC), and pregnancy results were recorded from the patients documents.
Results: The main complaint was infertility while 59.5% (n:28) of the patients had heavy menstrual bleeding. Overall 70.2% (n: 33) of the patients had a single leiomyoma. The mean leiomyoma size was 9.89 ± 2.87. There was no statistical significance between the pre-postoperative AMH values (p = 0.11). Pregnancy was achieved in 25.5% (n:12) of the patients followed up 1 year. Naturel conception occurred in 91.6% (n=11) patients after myomectomy. Out of the twelve pregnancies, eleven resulted in term pregnancy. Eighty-three % of the patients (10/12) who got pregnant were over 35 years of age.
Conclusion: AMH is an essential marker for ovarian reserve. It was observed that there was no decrease in AMH when a procedure that would disrupt ovarian blood supply was not applied during myomectomy. There was a significant increase in spontaneous pregnancy rate, especially in the secondary infertile group. This result was quite remarkable for AMH levels.
Anahtar Kelimeler: Laparotomy, uterine myomectomy, Anti-müllerian hormone (AMH), ovarian reserve, reproductive outcome