This study was conducted on 40 Samples of patients with polycystic ovary syndrome (PCOS) after their diagnosis, The study aimed to evaluate the lipid profile (triglycerides (TG), cholesterol (CH), low-density lipoprotein cholesterol (LDL-C), very low-density lipoprotein cholesterol (VLDL-C) and high-density lipoprotein cholesterol (HDL-C) associated with PCOS. Patients aged 19-45 years were included in the study and blood samples were taken during the menstrual cycle. Besides, 20 healthy controls were included to compare with PCOS. LDL-C, HDL-C, TG, and CH were significantly higher in the PCOS group than in the control group, whereas HDL-C was significantly lower in the PCOS group than in the control group (p <0.05). The results were distributed to three groups according to BMI, age and treatment. BMI was divided into three groups; BMI (18.5-24.9) (25.0-29.9) and (≥30) kg/m2. The results showed a highly significant increase (p≤0.05) in the LDL-C, HDL-C, TG, and CH compare to BMI (18.5-24.9) kg/m2 and (≥30) kg/m2. Age was divided into three groups (19-26) (27-35) (36-45) years. The results showed a significant increase (p≤0.05) in the age group (45-36) years compared with the age groups (26-19) years and (35-27) years. As for the cholesterol concentration, there were no significant differences between the studied age groups. The concentration of LDL-C showed a significant increase (p≤0.05) in the age groups (35-27) and (45 -36) compared with the age group (26-19 years). Treatment was divided into three groups according to metformin, progesterone contraceptive used and non-used of the treatment. Results showed a significant decrease in P≤0.05 level in infected women used for the treatment of metformin and progestogen contraceptives compared with infected women and without using any treatment in the concentrations of triglyceride, cholesterol, and low-density lipoprotein.
Anahtar Kelimeler: Polycystic Ovary Syndrome, Triglycerides, Cholesterol, Lipoprotein